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Composed of three amino acidscysteine, glutamine, and glycineglutathione helps neutralize free radicals, reduce oxidative stress, and support immune function

Dysfunctional mitochondria generate excessive reactive oxygen species (ROS), perpetuating a vicious cycle that further aggravates neurotoxicity (Yan et al., 2021

Evidence also suggests that mutant SOD1 attaches to key proteins involved in the cell death process further implicating mitochondria and apoptosis in ALS

In our study, oxidative damage in the form of intestinal protein carbonyls or TBARS was not detected when intestinal glutathione was depleted (BSO treated rats)