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Development of new drugs for COPD

It should be avoided in patients with allergies to its ingredients including wheat or gluten intolerance

In this review, examples will be discussed how experimental conditions (dose, solvent, etc.), the experimental system (species, strain, and substrain in vivo, cell type, and in vitro conditions), and also adaptive responses and off-target effects of genetic manipulations and chemical interventions, can impact the mechanisms of cell death