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Targeted delivery of p-coumaric acid encapsulated mannosylated liposomes to the synovial macrophages inhibits osteoclast formation and bone resorption in the rheumatoid arthritis animal model

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The transcription factor involved in response to amino acid starvation is activating transcription factor 4 (ATF4), which binds to the CSE promoter in addition to promoters of other amino acid biosynthetic and transport genes (Harding et al ., 2003)

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