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It is thought to involve aberrant immune responses but is not classified as a typical autoimmune disorder

Almost all hemolytic episodes related to altered HMP shunt and glutathione metabolism are due to G6PD deficiency, and this enzyme deficiency is known to affect millions of people throughout the world

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In this article, the biochemistry of persulfides is described, and the possible ways in which the formation of a persulfide could impact on the properties of the biomolecule involved are discussed