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Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis

Peer review Peer review information Nature Communications thanks Hongli Mao, and the other, anonymous, reviewer for their contribution to the peer review of this work

Oxidative stress is accepted to be the main contributing factor, with sperm quality and quantity affected by the overproduction of free radicals

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