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Melanocortin-Dependent Impairment of Glial Cells and its Consequences on Brain and Peripheral Function During Alcoholism Episodes of adolescent binge drinking could have long-term consequences that will affect not only the circuits involved in alcohol reward, but also those implicated in memory, learning and feeding behavior
However, CJC-1295 (especially the DAC version) can cause sustained elevation in IGF-1, whichif mismanagedmay increase the risk of: Insulin resistance Carpal tunnel syndrome Soft tissue growth (in rare, prolonged cases) Pituitary overstimulation That said, these issues are more often associated with excessive dosing or continuous high-frequency use
Helmich RC, Hallett M, Deuschl G, Toni I, Bloem BR