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Lightly cooking broccoli instead of fully cooking also increases the sulforaphane levels.[ref] Safety, timing, and dosage of sulforaphane supplements: As a natural part of cruciferous vegetables, sulforaphane is generally regarded as safe in low doses

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Curcumin can not only reduce the production of uric acid by inhibiting the activity of XO, alleviating the symptoms of hyperuricemia and gout to a certain extent [443, 444], but also inhibit the activity of inducible nitric oxide synthase, reducing the production of NO [445, 446]