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epithalon and epithalone) is a therapeutic tetrapeptide consisting of the amino acids alanine, glutamic acid, aspartic acid, and glycine

Therapeutic peptides are designed to treat specific medical conditions, while synthetic peptides are created to mimic the structure and function of natural peptides

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R 3 is NR 5 R 6 , C 1 -C 6 alkyl-NR 5 R 6 , C 1 -C 6 haloalkyl, C 1 -C 6 alkyl-OR S , optionally substituted C 1 -C 6 alkylC 3 -C 6 cycloalkyl, optionally substituted C 2 -C 7 heterocycloalkyl, C 1 -C 6 alkyl-0O 2 R 6 , C 1 -C 6 alkyl-C(O)NR 5 R 6 , or R 2 and R 3 together with the carbon atom to which they are attached form an optionally substituted C 2 -C 7 heterocycloalkyl ring