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Furthermore, iron chelators, such as deferoxamine (DFO), ciclopirox (CPX), and curcumin (Rainey et al., 2019) can reduce the concentration of Fe 2+ (Yang and Stockwell, 2008), suppressing ferroptosis

J Mol Cell Cardiol 41:762773

When you will notice changes

After treatment of 35 mg oral trimetazidine twice daily for 12 weeks, the oxidative stress markers, including malondialdehyde and 8oxodG, and the resting energy expenditure were reduced in patients with amyotrophic lateral sclerosis, which may affect the disease progression of amyotrophic lateral sclerosis [199]