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Meanwhile, under the harsh environment of long-term high blood glucose levels, accumulation of advanced glycation end products (AGEs) and high levels of reactive oxygen species (ROS) and inflammatory factors in diabetic wounds, the relevant cells involved in wound repair will be functionally impaired or even die, which seriously affects the normal healing process of wounds [11]

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Prior research has indicated that extracts derived from Astragalus, Epimedium, and Ligustrum had therapeutic and preventative properties that enhance stress tolerance, egg production, immunology, and intestinal health in pigeons (28)

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