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Examining the adaptive processes that are established to respond to the initial CS burden may help to understand what pathways become defective or are compromised and may contribute to the pathogenesis of COPD

Reduction in Sleep Latency: Patients report significantly faster onset of sleep following treatment, attributed to the reduction in neural hyperexcitability and enhanced thalamocortical inhibition

The narrative closes with a brief appraisal of unmet needs and translational prospects, underscoring how precision dosing, biomarker-guided stratification, and next-generation delivery systems could consolidate riboflavins place in neurotherapeutics

However, the current evidence base is largely preclinical, and no large-scale human clinical trials have confirmed its efficacy