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In this context, analytical methods such as HPLC peptide analysis and LC-MS verification can help evaluate purity, identity, molecular characteristics, and research material consistency

Here are some of the most common reasons for vitamin B12 deficiency: Pernicious Anemia This is the most common cause of vitamin B12 deficiency worldwide and mainly affects people of Northern European ancestry

Patients with long-standing alcohol use, restrictive diets, malabsorption syndromes, or prolonged use of medications that deplete or interfere with B vitamins may particularly benefit when a deficiency is confirmed

Early symptoms may be as subtle as feeling worn out and weak