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Symptoms of a B12 deficiency include: Excessive fatigue Nerve problems (pain or abnormal sensations like numbness or tingling) Glossitis (tongue inflammation) Low numbers of white blood cells and red blood cells Vitamin B12 deficiency can be diagnosed with a blood test

Afterward, the frequency of injections may be reduced to a maintenance schedule, typically once every two to four weeks

Berlin H, Berlin R, Brante G (1968) Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor

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