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Ficlatuzumab is currently being tested in combination with cetuximab in a Phase Ib clinical trial of recurrent and metastatic HNSCC (NCT02277197)

Serum B12 reference ranges vary between laboratories, but generally, levels below 148 pmol/L are considered deficient, whilst levels between 148258 pmol/L are regarded as borderline and may warrant further investigation or a trial of treatment, particularly if symptoms are present

Because they are commonly treated as complementary