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Research has found that exposing renal tubular epithelial cells to various concentrations of CaOx crystal solution results in a significant increase in the expression of ferroptosis-related proteins such as p53, ACSL4, transferrin receptor (TRC), and TF as the concentration of CaOx crystals increases

Studies indicate that DSIP can influence immune responses by regulating inflammatory pathways and maintaining a balance between pro-inflammatory and anti-inflammatory cytokines

In addition, histological analysis revealed a significant difference in liver damage between female and male L-DKO mice (Fig

This anti-lipogenic activity is hypothesized to involve inhibition of acetyl-CoA carboxylase, the rate-limiting enzyme in de novo lipogenesis