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Some people may feel a slight discomfort when the needle is inserted in the vein, or may experience bruising, itching, inflammation or redness at or around the infusion site, which disappears after a few minutes or several days

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Injury location: Well-vascularized areas like muscles heal faster than poorly vascularized tendons or ligaments

Similarly, although hepatic dysfunction can occur with large niacin doses (1-3 grams daily over months) causing elevated liver enzymes or jaundice, niacinamide at 100 mg is very unlikely to have any adverse effect on the liver