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Ample evidence suggests that an imbalance in dopaminergic tone impacts the expression levels of neuropeptides like somatostatin (SST) and neuropeptide Y (NPY), as seen in patients with Parkinsons disease and HD as well as in rodent models 15,16,17,18

Instead, patients often experience a complex constellation of neurological, cognitive, and immunological complaints that overlap with many other chronic conditions

The efficacy evidence is mixed, the effects fade quickly, and it has been linked to kidney, liver, and thyroid problems

The response was dose-dependent, meaning higher doses produced larger GH elevations within the studied ranges