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These peptides work fundamentally different than caffeine or stimulants

Delving deeper, it was suggested that Ipamorelin might interface with, and perhaps elevate, IGF-I concentrations

Moreover, hyperinsulinemia, a phenomenon associated with insulin resistance, results in high levels of insulin and glucose in blood, leading to an increase in the release of proinflammatory cytokines, promoting microglial proliferation and proinflammatory polarization in vivo (Yang et al., 2022)