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Therapeutic potential of alpha-1 antitrypsin in type 1 and type 2 diabetes mellitus

However, these mainstream therapies face critical limitations including the rapid emergence of drug resistance, FKS1/FKS2 gene mutations reducing -1,3-glucan synthase affinity, Targeted enzyme (Erg11p) modification, overexpression of efflux pumps (CDR1, MDR1), and upregulation of the ergosterol pathway mediate azole resistance (Pristov and Ghannoum, 2019)

Delaying treatment can reduce the likelihood of hearing recovery

Because its administered intravenously, the nutrients bypass the digestive system, allowing for higher concentrations to reach the cells quickly and efficiently