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In other words, the gastrointestinal side effects were milder and less frequent than what researchers typically see with GLP-1 and GIP agonists

This guide reflects CMS Billing and Coding Articles A58995 and A56681 and the NCCI PTP edit schedule updated as of June 2026

TIER 0 (18mg total) $195 total for 8-10 week supply Monthly cost breakdown: $78-$98 based on weekly dose Recommended if using low (or micro) doses of 2mg/week or less TIER 1 (44mg total) $229 total for 8-10 week supply Monthly cost breakdown: $92-$115 based on weekly dose Recommended if new to treatment or for those on 2-5mg/week TIER 2 (66mg total) $259 total for 8-10 week supply Monthly cost breakdown: $104-$130 based on weekly dose Recommended for those on 6-8mg/week TIER 3 (88mg total) $299 total for 8-10 week supply Monthly cost breakdown: $120-$150 based on weekly dose Recommended for those on 9-11mg/week TIER 4 (132mg total) $349 total for 8-10 week supply Monthly cost breakdown: $140-$175 based on weekly dose Recommended for those on 12mg/week and up Red Rock Pharmacy - Tirzepatide/B12 Injection & Tirzepatide/Glycine Injection Up to 90 days BUD

This requires carefully measuring powder, which is impractical for most researchers since the peptide comes in sealed vials