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Patients must understand that with all injection therapy, in general, there is improvement just over 60% of the time and that improvement in curvature may not mean that the patients difficulty with intercourse is fully addressed

Most research to date is in animal models

Treatment doses depend on the cause: pernicious anaemia typically requires intramuscular hydroxocobalamin 1,000 micrograms three times weekly initially, whilst dietary deficiency may be treated with oral cyanocobalamin 50150 micrograms or 1,000 micrograms daily

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