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doi: 10.1111/iwj.12904 54 HadianYBagoodMDDahleSESoodAIsseroffRR

The body has to break this version down before it can absorb the B12 vitamin

However, challenges remain in optimizing their cartilage-specific targeting in dense ECM environments, understanding their effects on synovial and subchondral tissues, and validating long-term therapeutic benefits in age-related or metabolic OA models