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Multi-dose preserved nasal sprays: Contain antimicrobial preservatives (most commonly benzalkonium chloride , typically 0.010.02% w/v, often with EDTA as a chelating agent)

Where the tonicity agent is sorbitol, it may be present in a concentration of about 10-40 mg/ml

Evidence Assessment for the Degradation Claim The scientific claim that mixing these peptides causes degradation due to pH incompatibility fails to meet evidentiary standards for several reasons: Structural incompatibility with the mechanism: The postulated copper-catalyzed oxidation pathway requires methionine or cysteine residues in the target peptides

There were no differences between the control and experimental groups during either phase