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Therefore, despite standard treatment, tumor recurrence occurs in many patients, which is mainly due to the cancer cells' ability to activate survival pathways and develop resistance to chemotherapy and radiation therapy

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The healthy third leaf from apex was taken into account for recording leaf gaseous exchange attributes like transpiration rates (E) (mmol H 2 O m 2 s 1 ), stomatal conductance (gs) (mmol H 2 O m 2 s 1 ), photosynthetic rate (PN) (mol CO 2 m 2 s 1 ) and water use efficiency (WUE)