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The cell-free supernatant was combined with a sulfhydryl preserving solution and assayed for glutathione content by HPLC and normalized based on the urea dilution method as described previously ( STATISTICS Nominal data are presented as means with SE and analyzed by ANOVA and Dunnets or Bennetts post hoc test as indicated
516,517 Knockdown of METTL3 promotes the expression of FSP1 and SLC7A11, whereas METTL3 overexpression aggravates cystine deprivation- and erastin-induced ferroptosis in human aortic smooth muscle cells (HASMCs), suggesting that METTL3 may promote ferroptosis in HASMCs primarily by inhibiting FSP1 and SLC7A11 expression
ETS-GS is a combination of vitamin E, taurine, and GSH that showed protective effects with various models of ischemia/reperfusion and inflammation (Sugita et al., 2013)
McMurtrey has since replicated this work in his own lab, taking adult blood cells and reprogramming them back into pluripotent stem cells, then differentiating and directing them to reconstruct new 3D tissue types using a variety of biochemical, biomechanical, and nanopatterning cues [105-111]
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