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If the proposed mechanism (gradual synaptic plasticity effects) is right, daily dosing might be needed for sustained effect

Route of Administration How a peptide is delivered dramatically affects how long it stays in the body: Subcutaneous injection : slower absorption, longer duration Intramuscular injection : faster peak concentration, moderate duration Oral and intranasal peptides : often rapidly broken down, requiring protective technologies or higher doses For example, oral BPC-157 may work primarily through gut-localized pathways, while injectable versions may provide broader systemic benefits

The multi-system approach and neuroprotective effects contrast with SSRIs primary focus on serotonin reuptake

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