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The lipid peroxidation, ROS burst, and iron release associated with ferroptosis may further promote NETosis, thereby generating a cascade amplification effect that exacerbates periodontal connective tissue degradation and bone resorption ( in vivo evidence for neutrophil ferroptosis in periodontitis remains limited, and its pathological contribution is primarily achieved indirectly through NETosis

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Furthermore, roe from non-sturgeon species is widely used as a less costly caviar substitute and is preferentially named roe rather than caviar 1