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According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

K., Plutzky, J., van Beek, A

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B-vitamin supplementation may slightly reduce risk of stroke, but these benefits may not be seen in patients with chronic kidney disease