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As a precaution, milk thistle should not be taken while taking medication, or only after consulting a doctor

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The recommended vitamin B12 intake (in micrograms, or mcg) is as follows: *Adequate Intake S ource: National Institutes of Health Office of Dietary Supplements Unless you have a B12 deficiency or have identified a risk factor for deficiency (like following a vegan diet or having a malabsorption issue), theres no need to take a vitamin B12 supplement