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Abstract First, we review the definitively severed myotendinous junction and recovery by the cytoprotective stable gastric pentadecapeptide BPC 157 therapy, its healing that might combine both transected and detached tendon and transected muscle, ligament and bone injuries, applied alone, as native peptide therapy, effective in rat injury, given intraperitoneally or in drinking water or topically, at the site of injury

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In general, a plan of 5-6 injections within 6-8 weeks is recommended

Nevertheless, one should keep in mind that small changes in DNA methylation (situated on only one or a few not densely packed CGs) might not be detected by genome-wide DNA methylation profiling methods, such as the methyl-cytosine immunoprecipitation and reduced-representation bisulfite sequencing used in the above-mentioned studies (Fouse et al., 2008