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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action Glutathione (-L-glutamyl-L-cysteinyl-glycine) acts as a redox buffer, maintaining intracellular thiol equilibrium

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Kidney: DAO is also produced in the kidneys, where it contributes to histamine metabolism and helps maintain proper histamine levels in the body

Given the strong link found between low body mass index and decreased survival with ALS (Paganoni et al., 2011), a randomized double blind phase 2 clinical study was performed in small number of patients with ALS to test the safety and tolerability of high caloric diets, which were either high in carbohydrates or high in fat