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1e): 3,9,14,15,30,34,46,57,60 (i) The thiolate of the reduced monothiol class I glutaredoxin directly attacks the disulfide substrate followed by the stepwise reduction of the mixed disulfide and Grx(SSG) by two molecules of GSH

Meanwhile, novel molecular biology and computational informatics methods unveil the complexity of physiological processes and the plethora of new mediators of their intra- and inter-cellular communications within neuroendocrine-immune and cardiovascular systems