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This pressure can result in lid tenderness and inflammation, gland shortening, atrophy and loss, recurrent eyelid infections (stye, hordeola, chalazia, cellulitis), and the classic symptoms of ocular irritation associated with dry eye, Meibomian gland dysfunction, blepharitis, and ocular rosacea

NICE technology appraisal TA875 (2023) recommends semaglutide 2.4 mg (Wegovy) as an adjunct to a reduced-calorie diet and increased physical activity for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when initiated within specialist weight management services