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Cyanocobalamin is the most commonly used form of vitamin B12 in supplements and injections, while methylcobalamin is a more natural form of vitamin B12 that is found in some foods

The right protocol depends on the patients health history, symptoms, goals, labs, and medical candidacy

doi: 10.3389/fmolb.2025.1639327 Received 07 June 2025 Accepted 04 July 2025 Published 22 July 2025 Volume 12 - 2025 Edited by Venkaiah Betapudi, United States Department of Health and Human Services, United States Reviewed by Anderson Oliveira Souza, Federal University of Mato Grosso, Brazil Raffaella Scanga, University of Calabria, Italy Danish Idrees, University of Iowa Healthcare, United States Rahul Patil, Augusta State University, United States Updates Copyright 2025 Seneff and Kyriakopoulos

10.1172/JCI90519 113 SangkhaeV.FisherA