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In the central nervous system, the main synthesis pathway of DA is from L-tyrosine, which is transformed into L-dopa by tyrosine hydroxylase (TH) and then decarboxylated by aromatic acid decarboxylase (AADC) in the iron and H4-biopterin dependent pathway to produce DA

You may be more likely to have Barretts esophagus if you have a history of chronic acid reflux (GERD), smoking and/or drinking

Enhancing mitochondrial function is the wellspring of efforts to optimize physical fitness and longevity at the cellular level