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( F ) Mean GSH/GSSG ratios in A549shNRF2-BIND-luc, -BIND-WT NRF2, -BIND-Neh4/5mut cells treated with water (control) or 2.5 ng/mL dox for 48 h

More globally, analysis of GPX4 protein expression levels performed in up to forty different cancers show that besides AML, GPX4 is also elevated in most hematological malignancies including Acute Lymphoblastic Leukemia (ALL), Multiple Myeloma (MM) and Non-Hodgkin's Lymphoma (NHL) [39]