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Studies have shown that some compounds exhibit significantly greater antioxidant effects in vivo than suggested by in vitro results, underscoring the importance of biological context (Zahra et al., 2022

- Incompatibilidad qumica : cido ascrbico reduce Cu a Cu, disociando el complejo

A secondary finding was that NAA was significantly reduced across cortical regions after excluding outlier datasets

It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)