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For remaining experiments adult animals at an age of 1012 weeks were used

doi: 10.1016/j.cell.2010.03.014 29 GeeraertsXet al

Many new questions about the mechanism of DNA methylation-mediated gene expression regulation in mammals have appeared: (i) what is the role of non-CG methylation in stem cells, in which it appears enriched on transcribed strands of gene bodies of highly active genes (Lister et al., 2009), and does it occur in different cell types as suggested in some studies