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The compound remains detectable in urine for up to 4 days by mass spectrometry methods, despite its short plasma half-life, suggesting tissue distribution and binding may extend its biological effects beyond plasma clearance times

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Although the serum glycerol levels were similarly increased in WT/HFD mice and Insr P1195L/ +/HFD mice, the blood glucose levels after CL316432 administration were significantly higher in Insr P1195L/ +/HFD mice, indicating that enhanced lipolysis exacerbates hyperglycemia in Insr P1195L/ +/HFD mice

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