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These two approaches substrate supplementation and enzyme inhibition can be considered conceptually complementary, but they are mechanistically distinct

The hepatoprotective effects of NaBPC157 were evaluated in comparison with reference standards such as bromocriptine, amantadine and somatostatin in various experimental models of liver injury in rats: 24 hour-bile duct and hepatic artery ligation, 48 hour-restraint stress and CCl 4 (a free radicals inducing agent) administration

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Insertion of amide bonds at various locations in the carbon chain was not productive