In order to create a personalized, case-specific preventive and patient profile, it is essential to take a detailed medical history and perform diligent examination of the general medical and intraoral health, as well as considering the two in combination (Fig
However, the health burden from SHS is expected to be relatively low, as it is estimated to account for less than 10% of the disability-adjusted life years attributable to active smoking in Italy 3

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In August 2016, OEHHA adopted new regulations, effective on August 30, 2018, which change the information required in Proposition 65 warnings