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That exceeds the results from every other weight loss medication tested in clinical settings, including Tirzepatide at 20.9% and Semaglutide at 14.9%

Increased permeability of the gut barrier has been observed to occur with a variety of physiological stressors including heat stress [4, 5], exercise stress [6], psychological stress [7], excessive dietary fat intake [8], lack of fibre [9], and sleep deprivation [10] many of these are also risk factors for hypertension [11, 12]

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Bayomy O, Zaheer S, Williams JS et al (2020) Disentangling the relationships between the renin-angiotensin-aldosterone system, calcium physiology, and risk for kidney stones