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10.3389/fpsyt.2022.889636 108 NathanC.Cunningham-BusselA

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In response to the rapidly growing public health crisis of thousands of citizens self-injecting completely unregulated, potentially contaminated products, the MHRA has initiated widespread investigations into aesthetic clinics and has executed coordinated raids on illicit manufacturing facilities suspected of synthesizing illegal peptide medications

This review uniquely juxtaposes these disorders, proposing that despite discrepant etiologies, early-life nutritional imbalances whether deficiency or excess, converge on common endocrine, immunological, epigenetic and gut-microbiome-related pathways and metabolic outcomes, with intergenerational implications