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Madeo F, Herker E, Maldener C, Wissing S, Lchelt S, Herlan M, et al

Reduced intestinal motility, mucosal barrier function, and inflammation in aged monkeys

The model was founded through long-term oscillating glucose (LOsG) intake and the setup of a sham group and a glutathione intervention group

Clinical therapy of targeting ferroptosis in human diseases Numerous preclinical studies have demonstrated that iron acts as a potent pro-oxidant, contributing to the development and progression of tumors, central nervous system diseases, metabolic diseases, autoimmune diseases, and cardiovascular diseases through the production of highly reactive and cytotoxic free radicals