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Optimising Levels: In cases where B12 levels, despite injections, arent quite reaching the optimal range, a GP might suggest adding a daily oral supplement to top up levels, especially if theres some residual capacity for passive absorption

You will need to be careful to avoid interactions with other drugs, particularly those that treat various digestive issues

You shouldnt take acid-reducing medications for long since it can affect how your body absorbs B12

What the Authoritative Sources Say About B12 Deficiency and Supplementation The National Institutes of Health Office of Dietary Supplements publishes the most thorough citation-backed overview of vitamin B12 its role in red blood cell formation and neurological function, the populations most at risk for deficiency (older adults, people on long-term metformin or proton pump inhibitors, vegetarians and vegans, people who have had gastric bypass surgery), and the recommended daily intake at each life stage