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O 2 , produced by the mitochondrial electron transport chain or by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NO x ) activity
Some men cannot tolerate these medications because of the side-effects which include dizziness, headaches, and sexual dysfunction
These medications often produce more immediate, powerful sedation but can disrupt normal sleep architecture, reduce deep sleep, and cause dependency with regular use
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