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Establishing unified and standardized OA animal models, local administration protocols, and comprehensive efficacy evaluation systems will be key to promoting the translation of ferroptosis-targeted therapies from the laboratory to the clinic

To better understand the role of immune mechanisms in the formation of NETs and the processes related to the generation of free radicals during miscarriage, we decided to expand our study by assessing the concentrations of nicotinamide adenine dinucleotide phosphate oxidase 1 (NOX1), which is one of the isoforms of nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), and that of NCF2 (neutrophil cytosolic factor 2, NOXA2), which is an integral protein of the NADPH oxidase (Chocry and Leloup 2020)

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Keep in mind it comes as a 30 mL multi-use vial, should not be used in newborns, and should not be injected intravenously by itself due to its hypotonicity