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They are permeable to sodium and potassium ions and are responsible for the rapid depolarization of the postsynaptic membrane that underlies the excitatory postsynaptic potential (EPSP)

Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor- by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro

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Jaishankar M, Tseten T, Anbalagan N, Mathew BB, Beeregowda KN