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10.1038/ajg.2013.304 Am

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That decline maps almost exactly to the slow metabolic decay people complain about in their 40s and 50s

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In women with episodic migraines ( n = 92), ALA (300 mg twice daily) for 12 weeks significantly reduced migraine severity and frequency, and reduced serum lactate and vascular cell adhesion molecule-1, suggesting improvement in mitochondrial and endothelial function, respectively

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