As we analyzed the correlation between CK5 expression and age, cigarette smoke (pack/years) and lung function parameters in smokers with and without COPD separately, we found that the expression of this marker was negatively correlated with age ( r = 0.334, p = 0.047), and positively associated with FVC ( r = 0.335, p = 0.046) in only BEC cultures of COPD patients (Supplementary Figure S2)
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